Akademik Veri Yönetim Sistemi
Istanbul Tip Fakultesi Mecmuasi, cilt.57, sa.4, ss.74-77, 1994 (Scopus)
Chronic autoimmune idiopathic thrombocytopenic purpura has been rarely reported with another autoimmune disease, Type 1 diabetes mellitus in the literature. In this study a case report of a twelve year-old girl who has both diseases is presented. Clinical and laboratory findings resulted during the immunosuppressive treatment are also given, This particular patient showed a clinical feature characterized with diabetic ketoacidosis, and thrombocytopenia with an antibody to thrombocytes and increased mega caryocytes on bone marrow aspiration sample. Following the control of the diabetic status by intensive insulin therapy (0.90 IU/kg/day), prednisolone (0.70 mg/kg/day p.o.) and high dose gammaglobulin (1 gr/kg/day i.v. in 5 days cure) were applied. However, a splenectomy was performed due to insufficient response to medical therapy. Observation of simultaneous short duration complete remissions of both autoimmune disorders during follow-up period were found.