Relapse of hepatitis B in HBeAg-negative chronic hepatitis B patients who discontinued successful entecavir treatment: The case for continuous antiviral therapy

Shouval, Daniel; Lai, Ching-Lung; Chang, Ting-Tsung; Cheinquer, Hugo; Martin, Paul; Carosi, Glamplero; Han, Steven; Kaymakoglu, Sabahattin; Tamez, Ricardo; Yang, Joanna; Tenney, Daniel; Brett-Smith, Helena

doi:10.1016/j.jhep.2008.10.017

Relapse of hepatitis B in HBeAg-negative chronic hepatitis B patients who discontinued successful entecavir treatment: The case for continuous antiviral therapy

Shouval D., Lai C., Chang T., Cheinquer H., Martin P., Carosi G., ...Daha Fazla

JOURNAL OF HEPATOLOGY, cilt.50, sa.2, ss.289-295, 2009 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 50 Sayı: 2
Basım Tarihi: 2009
Doi Numarası: 10.1016/j.jhep.2008.10.017
Dergi Adı: JOURNAL OF HEPATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.289-295
İstanbul Üniversitesi Adresli: Hayır

Özet

Background/Aims: To evaluate the off-treatment durability of response in HBeAg-negative chronic hepatitis B patients who achieved a protocol-defined 'Response' (HBV-DNA < 0.7 MEq/mL and ALT < 1.25 x ULN) with entecavir at 48 weeks and the efficacy of entecavir in patients treated beyond one year.