Relapse of hepatitis B in HBeAg-negative chronic hepatitis B patients who discontinued successful entecavir treatment: The case for continuous antiviral therapy


Shouval D., Lai C., Chang T., Cheinquer H., Martin P., Carosi G., ...More

JOURNAL OF HEPATOLOGY, vol.50, no.2, pp.289-295, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1016/j.jhep.2008.10.017
  • Journal Name: JOURNAL OF HEPATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.289-295
  • Istanbul University Affiliated: No

Abstract

Background/Aims: To evaluate the off-treatment durability of response in HBeAg-negative chronic hepatitis B patients who achieved a protocol-defined 'Response' (HBV-DNA < 0.7 MEq/mL and ALT < 1.25 x ULN) with entecavir at 48 weeks and the efficacy of entecavir in patients treated beyond one year.