Serum chitotriosidase activity in patients with coronary artery disease

Karadag B., Kucur M., ISMAN F. K., Hacibekiroglu M., Vural A. V.

CIRCULATION JOURNAL, vol.72, no.1, pp.71-75, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 72 Issue: 1
  • Publication Date: 2008
  • Doi Number: 10.1253/circj.72.71
  • Journal Name: CIRCULATION JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.71-75
  • Istanbul University Affiliated: Yes

Abstract

Background Atherosclerosis is considered to be an inflammatory disease in which the initial process is augmented infiltration of monocytes into the vessel wall and their subsequent differentiation from macrophages into lipid-laden foam cells. Chitotriosidase is one of the most quantitative proteins secreted by activated macrophages, so the aim of this study was to investigate the association of the level of serum chitotriosidase activity with atherosclerotic coronary artery disease (CAD).