Serum chitotriosidase activity in patients with coronary artery disease

Karadag B., Kucur M., ISMAN F. K., Hacibekiroglu M., Vural A. V.

CIRCULATION JOURNAL, cilt.72, sa.1, ss.71-75, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 72 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1253/circj.72.71
  • Dergi Adı: CIRCULATION JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.71-75
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background Atherosclerosis is considered to be an inflammatory disease in which the initial process is augmented infiltration of monocytes into the vessel wall and their subsequent differentiation from macrophages into lipid-laden foam cells. Chitotriosidase is one of the most quantitative proteins secreted by activated macrophages, so the aim of this study was to investigate the association of the level of serum chitotriosidase activity with atherosclerotic coronary artery disease (CAD).