Histopathologic Changes in the Middle Ear Mucosa After Exposure to Pepsin and Unconjugated Bile Acid


DEVELIOGLU O. N. , YALCIN E., Bulut E., CELEBI S., SAHAN E., Ustundag N. , ...More

JOURNAL OF CRANIOFACIAL SURGERY, vol.25, no.6, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 6
  • Publication Date: 2014
  • Doi Number: 10.1097/scs.0000000000001041
  • Title of Journal : JOURNAL OF CRANIOFACIAL SURGERY

Abstract

Objective: An increasing number of studies indicate that pepsin and bile acid cause damage to the ear, nose, and throat structures as a result of extraesophageal reflux. The aim of this study was to evaluate and compare the damaging effect of bile acids and pepsin on the middle ear mucosa.