Endocrine late effects of childhood cancer therapy

POYRAZOĞLU Ş., BAŞ F., Darendeliler E., DARENDELİLER F. F.

TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY, vol.25, no.1, pp.37-46, 2010 (ESCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 25 Issue: 1
  • Publication Date: 2010
  • Journal Name: TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.37-46
  • Keywords: Childhood cancer, endocrine late effects, chemotherapy, radiotherapy, FUNCTION FOLLOWING CHEMOTHERAPY, LONG-TERM SURVIVORS, ACUTE MYELOID-LEUKEMIA, GROWTH-HORMONE, HODGKINS-DISEASE, GONADAL-FUNCTION, THYROID-DYSFUNCTION, TESTICULAR FUNCTION, CRANIAL IRRADIATION, PITUITARY-FUNCTION
  • Istanbul University Affiliated: Yes

Abstract

Survival rates are improving following effective cancer therapy in childhood cancer. As the number of childhood cancer survivors increases, the late effects of cancer therapy are encountered more frequently. Endocrine disorders are prominent among the late effects. The recognition and prompt management of these endocrine late effects are essential to prevent further morbidity and impairment of quality of life. The aim of this article was to investigate these late effects of chemotherapy and/or radiotherapy for each endocrine system.