A rare case of Growing Teratoma Syndrome ; third recurrence after 13 years with liver metastases ; a case report and review of the literature

Selek S. B., Yumru Çeliksoy H., Kızıldağ Yırgın İ., Sözen H., Topuz S.

Türk Jinekolojik Onkoloji Dergisi , cilt.24, sa.1, ss.34-39, 2024 (Hakemli Dergi)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 24 Sayı: 1
  • Basım Tarihi: 2024
  • Dergi Adı: Türk Jinekolojik Onkoloji Dergisi
  • Sayfa Sayıları: ss.34-39
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: The growing teratoma syndrome (GTS) defined as the growth of a benign tumor after removal of a germ cell tumor or after chemotherapy. There is no reached consensus managing GTS.
Case: A patient had undergone surgery for an adnexial mass at the age of 14 and diagnosed with immature teratoma. 13 years after the last operation she underwent a fourth time tumor free fertility sparing operation with partial resection of the right liver lobe, partial resection of the peritoneum of diaphragm and cyst removal from right ovary. Pathology result was compatible with mature teratoma having no immature characteristics. To our knowledge, this is the first case reported in the literature that reoccured such a long time after the last GTS surgery such as 13 years and having benign features on histopathological examination.
Conclusion: GTS has an unpredictable behavior and could reoccur even after a very long time and several surgeries.