In Vitro Evaluation of the Toxicity of Cobalt Ferrite Nanoparticles in Kidney Cell

Abudayyak M. F., Altincekic Gurkaynak T., Ozhan G.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.14, no.2, pp.169-173, 2017 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.4274/tjps.99609
  • Journal Name: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.169-173
  • Keywords: DNA damage, cell death, apoptosis, cobalt ferrite nanoparticle, OXIDE NANOPARTICLES, COMET ASSAY, DNA-DAMAGE, GENOTOXICITY, REPAIR
  • Istanbul University Affiliated: Yes

Abstract

Objectives: The remarkable properties of hard magnetic cobalt ferrite nanoparticles (CoFe2O4-NPs) and their physicochemical stability lead to various applications in different industrial and medical fields. Although CoFe2O4-NPs have been reported to cause toxic effects, there is a serious lack of information concerning their effects on the kidneys. In this study, it was aimed to investigate the toxic effects of CoFe2O4-NPs on NRK-52E kidney cells.