In Vitro Evaluation of the Toxicity of Cobalt Ferrite Nanoparticles in Kidney Cell

Abudayyak M. F., Altincekic Gurkaynak T., Ozhan G.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.14, sa.2, ss.169-173, 2017 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/tjps.99609
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.169-173
  • Anahtar Kelimeler: DNA damage, cell death, apoptosis, cobalt ferrite nanoparticle, OXIDE NANOPARTICLES, COMET ASSAY, DNA-DAMAGE, GENOTOXICITY, REPAIR
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objectives: The remarkable properties of hard magnetic cobalt ferrite nanoparticles (CoFe2O4-NPs) and their physicochemical stability lead to various applications in different industrial and medical fields. Although CoFe2O4-NPs have been reported to cause toxic effects, there is a serious lack of information concerning their effects on the kidneys. In this study, it was aimed to investigate the toxic effects of CoFe2O4-NPs on NRK-52E kidney cells.