Heart rate variability in diabetes patients

Kudat H., AKKAYA V. A., SOZEN A. B., SALMAN S., DEMIREL S., OZCAN M., ...Daha Fazla

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, cilt.34, sa.3, ss.291-296, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1177/147323000603400308
  • Dergi Adı: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.291-296
  • Anahtar Kelimeler: diabetes mellitus, autonomic neuropathy, chronic complications, heart rate variability, CARDIOVASCULAR AUTONOMIC NEUROPATHY, IDDM PATIENTS, INSULIN, COMPLICATIONS, DYSFUNCTION, RETINOPATHY, MELLITUS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Diabetes mellitus can cause cardiovascular autonomic neuropathy and is associated with increased cardiovascular deaths. We investigated cardiovascular autonomic neuropathy in diabetics and healthy controls by analysis of heart rate variability. Thirty-one diabetics and 30 age- and sex-matched controls were included. In the time domain we measured the mean R-R interval (NN), the standard deviation of the R-R interval index (SDNN), the standard deviation of the 5-min R-R interval mean (SDANN), the root mean square of successive R-R interval differences (RMSSD) and the percentage of beats with a consecutive R-R interval difference > 50 ms (pNN50). In the frequency domain we measured high-frequency power (HF), low-frequency power (LF) and the LF/HF ratio. Diabetes patients had lower values for time-domain and frequency-domain parameters than controls. Most heart rate variability parameters were lower in diabetes patients with chronic complications than in those without chronic complications.