Investigation of JAM-A (rs790056) and LFA-1 (rs8058823) gene variants in Turkish colorectal cancer patients

Caykara B., Alsaadoni H., Pence H. H., Pence S., Aydogan H., Tastekin D.

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.30, sa.10, ss.872-876, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 10
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/tjg.2019.19141
  • Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.872-876
  • Anahtar Kelimeler: Colorectal cancer, rs8058823, rs790056, variation, JUNCTIONAL ADHESION MOLECULE, DISEASE, POLYMORPHISMS, PREVENTION, MODULATION
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background/Aims: Lymphocyte function-associated antigen 1 (LFA-1) is a transmembrane glycoprotein expressed on the surface of leukocytes and containing the binding domain for junctional adhesion molecule-A (JAM-A). The aim of the present study was to evaluate the effects of JAM-A and LFA-1 variants on the formation of colorectal cancer and metastasis.