Analysis of L-MYC gene polymorphism in patients with renal failure outcome to renal transplant
TRANSPLANTATION PROCEEDINGS, cilt.38, sa.5, ss.1267-1269, 2006 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 38 Sayı: 5
- Basım Tarihi: 2006
- Doi Numarası: 10.1016/j.transproceed.2006.03.037
- Dergi Adı: TRANSPLANTATION PROCEEDINGS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1267-1269
- İstanbul Üniversitesi Adresli: Evet
Özet
Background. Abnormalities of cell numbers and apoptosis have been observed in renal failure. As uncontrolled expression of c-myc is known to induce apoptosis, we thought that polymorphism in the other myc gene, L-myc gene, which is structually similar to c-myc and reported to be expressed in the kidney, may have a role in the induction of apoptosis and thus have role in chronic renal failure. The aim of this study was to investigate the relationship between the distribution of L-myc genotypes and renal failure.