Being ambulatory does not secure respiratory functions of Duchenne patients.


Ekici B. , Ergul Y. , Tatli B., Bilir F., Binboga F., Suleyman A. , ...More

Annals of Indian Academy of Neurology, vol.14, no.3, pp.182-4, 2011 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 3
  • Publication Date: 2011
  • Doi Number: 10.4103/0972-2327.85889
  • Title of Journal : Annals of Indian Academy of Neurology
  • Page Numbers: pp.182-4

Abstract

Aim: The aim of this work was to assess the respiratory functions of ambulatory Duchenne patients and to propose an earlier time period for intervention. Materials and Methods: Lung functions and North Star Ambulatory Assessment (NSAA) scores of Duchenne patients were evaluated simultaneously. Results: Thirty ambulatory Duchenne patients were included in this study. NSAA scores of the patients were directly correlated with arm abduction, arm adduction, and shoulder flexion strengths. Forced expiratory volume in 1 second percent predicted and forced vital capacity (FVC) percent predicted correlated inversely to age and to the NSAA score. Twelve of 13 patients with FVC values lower than 80% of predicted had NSAA scores below 24 points. None of the patients who were younger than 7 years had FVC values lower than 80% of predicted. Conclusion: Annual spirometry is necessary for Duchenne patients older than 6 years regardless of the ambulatory status.