Potentially inappropriate medication use by TIME criteria in nursing home residents and its relationship with common geriatric syndromes

Yildiz Y., Durmuş N. Ş., Bütün V. K., Inan B. D., Numanoğlu B. K., Çelenk M. E., ...Daha Fazla

European Geriatric Medicine, 2025 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1007/s41999-025-01344-3
  • Dergi Adı: European Geriatric Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Anahtar Kelimeler: Comprehensive geriatric assessments, Inappropriate medication use, Older adults, Polypharmacy, Turkish Inappropriate Medication Use in oldEr adults criteria
  • İstanbul Üniversitesi Adresli: Evet

Özet

Aim: To assess potentially inappropriate medication use (IMU), including both potentially inappropriate prescribing (PIP) and prescribing omissions (PPOs) according to the Turkish Inappropriate Medication Use in oldEr adults (TIME) criteria in older nursing home residents and to investigate its association with common geriatric syndromes. Findings: Both PIPs and PPOs were frequent in older adults, being associated with polypharmacy and frailty, respectively. Common issues included unnecessary antihypertensives, use of neuroleptics as hypnotics, proton pump inhibitor use, and missed treatments for dementia and malnutrition. Message: Polypharmacy and IMU were highly prevalent among older nursing home residents. Our findings emphasize that geriatric syndromes—particularly frailty—were strongly associated with PPOs, as identified by the TIME-to-START criteria.