Objective: Sepsis is a syndrome of physiologic, pathologic, and biochemical abnormalities that is induced by infection. Sepsis constitutes 5,2% of total hospital and 0,4% of emergency department admissions, and has high mortality rates (as high as 28%). Materials and Methods: In the application to the emergency department, patients’ comorbid disorders and demographic information indicated by patients and their relatives; blood pressure, pulsation, body temperature, respiratory rate, white blood cell count, platelet count, bilirubin level, creatinine level, urine output; and GCS score, SIRS criteria, SOFA and qSOFA scores and culture results were saved to the form prepared for the study. Results: 59% of the patients were male and 41% of them were female. Mean age of the patients was 62,25±16,48 years. According to diagnosis, SIRS criteria and SOFA scores had higher sensitivity rate than qSOFA scores. According to the mortality, SOFA score had highest sensitivity and NPV, qSOFA had highest specificity and PPV. SIRS criteria, SOFA and qSOFA scores and mortality rate were examined, there was a moderate positive relationship (r=0.44) only between SOFA scores and mortality rate. Conclusion: As a result it was concluded that usage of qSOFA scores is more optimal in emergency department for giving fast decision. However it was found that the qSOFA scores have low sensitivity for diagnosis and prediction of the mortality.