OUTCOMES OF SURGICAL TREATMENTS FOR HYPERTHYROIDISM IN 1308 PATIENTS – SINGLE CENTER EXPERIENCE

İşcan A. Y., Aktı N. E., Yanık M., Sormaz İ. C., Aksakal N., Şenyürek Y.

10th Biennial Congress of the European Society of Endocrine Surgeons (ESES), Rome, İtalya, 23 - 25 Mayıs 2024, (Yayınlanmadı)

  • Yayın Türü: Bildiri / Yayınlanmadı
  • Basıldığı Şehir: Rome
  • Basıldığı Ülke: İtalya
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background

To investigate the extent of thyroidectomy during the former and latter time frames of the study as well as the rate of thyroid cancer (TC) and morbidity in patients with hyperthyroidism (HT).

Method

Records of 1308 patients who underwent surgery for Graves’ disease (GD) (n=591), toxic multinodular goiter (TMNG) (n=495), and toxic adenoma (TA) (n=222) between 1992 and 2022 were retrospectively analyzed.

Results

Thyroid cancer was found in 16.8% of patients; the incidence was 14%, 21%, and 14% in GD, TMNG, and TA, respectively. The majority (75%) of TC was papillary microcarcinoma (PMC). The rates of TC >1 cm in the GD, TMNG, and TA groups were 2.9%, 6%, and 3.6%, respectively.

The incidence of TC in GD with coexistent nodules vs. with no nodules was 20% vs. 9%. In TA patients, TC >1 cm was found within the TA in 5 patients (2.2%). In TA patients with coexisting nodules, the TC rate was 24.4%.

The rates of temporary and permanent hypoparathyroidism and vocal cord palsy were 21% and 2.2%, and 6% and 1%, respectively.

Conclusion

The overall rate of TC >1 cm was 4% in all hyperthyroid patients; the majority of TC coexisting with HT was PMC. The patients with TMNG had the highest rate of TC >1 cm. The rate of less than total thyroidectomy (TT) significantly decreased in the latter period compared with the former period of the study.

Background

To investigate the extent of thyroidectomy during the former and latter time frames of the study as well as the rate of thyroid cancer (TC) and morbidity in patients with hyperthyroidism (HT).

Method

Records of 1308 patients who underwent surgery for Graves’ disease (GD) (n=591), toxic multinodular goiter (TMNG) (n=495), and toxic adenoma (TA) (n=222) between 1992 and 2022 were retrospectively analyzed.

Results

Thyroid cancer was found in 16.8% of patients; the incidence was 14%, 21%, and 14% in GD, TMNG, and TA, respectively. The majority (75%) of TC was papillary microcarcinoma (PMC). The rates of TC >1 cm in the GD, TMNG, and TA groups were 2.9%, 6%, and 3.6%, respectively.

The incidence of TC in GD with coexistent nodules vs. with no nodules was 20% vs. 9%. In TA patients, TC >1 cm was found within the TA in 5 patients (2.2%). In TA patients with coexisting nodules, the TC rate was 24.4%.

The rates of temporary and permanent hypoparathyroidism and vocal cord palsy were 21% and 2.2%, and 6% and 1%, respectively.

Conclusion

The overall rate of TC >1 cm was 4% in all hyperthyroid patients; the majority of TC coexisting with HT was PMC. The patients with TMNG had the highest rate of TC >1 cm. The rate of less than total thyroidectomy (TT) significantly decreased in the latter period compared with the former period of the study.