Caregiver burden and related factors in caregivers of patients with childhood-onset systemic lupus erythematosus

UZUNER S., Durcan G., Sahin S., Bahali K., Barut K., KILIÇOĞLU A. G., ...More

CLINICAL RHEUMATOLOGY, vol.40, no.12, pp.5025-5032, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 12
  • Publication Date: 2021
  • Doi Number: 10.1007/s10067-021-05867-5
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.5025-5032
  • Keywords: Caregiver burden, Children, Depression, Lupus, Psychopathology, DISEASE-ACTIVITY INDEX, CHILDREN, CARE, PARENTS, MOTHERS, PREDICTORS, INVENTORY, STRESS
  • Istanbul University Affiliated: Yes


Objective Having a child with a chronic illness is a source of stress for the whole family, especially the primary caregiver. The aim of this study was to evaluate the associations between caregiver burden and both the caregiver's and child's psychological symptoms in a cohort of children with systemic lupus erythematosus (SLE). Methods Thirty-four patients (aged 9-18 years) with childhood-onset SLE and their caregivers participated in this study. The control group was composed of healthy children and their caregivers. Questionnaires were used to evaluate caregiver burden and the psychological status of parents and children and adolescents with and without SLE. Results No significant difference was found between the study and control groups for caregiver burden, anxiety and depression in parents, and psychological status in children. Caregiver burden was positively correlated with parent's depression, anxiety, and behavioral and peer problems of the children, and it was negatively correlated with the children's prosocial behaviors. According to regression analyses, the parents' depression and children's peer relationship had a positive effect on caregiver burden scores. Conclusion Physicians should be aware of the presence of psychological symptoms in patients with childhood-onset SLE and their caregivers because it can affect caregiver burden and the caregiver's psychological state.