Prokineticin receptor-1 induces neovascularization and epicardial-derived progenitor cell differentiation
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, vol.28, no.5, pp.841-849, 2008 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 28 Issue: 5
- Publication Date: 2008
- Doi Number: 10.1161/atvbaha.108.162404
- Journal Name: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.841-849
- Istanbul University Affiliated: No
Abstract
Objective-Identification of novel factors that contribute to myocardial repair and collateral vessel growth hold promise for treatment of heart diseases. We have shown that transient prokineticin receptor-1 (PKR1) gene transfer protects the heart against myocardial infarction in a mouse model. Here, we investigated the role of excessive PKR1 signaling in heart.