Prokineticin receptor-1 induces neovascularization and epicardial-derived progenitor cell differentiation


Urayama K., Guilini C., Turkeri G., Takir S., Kurose H., Messaddeq N., ...Daha Fazla

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, cilt.28, sa.5, ss.841-849, 2008 (SCI-Expanded) identifier identifier identifier

Özet

Objective-Identification of novel factors that contribute to myocardial repair and collateral vessel growth hold promise for treatment of heart diseases. We have shown that transient prokineticin receptor-1 (PKR1) gene transfer protects the heart against myocardial infarction in a mouse model. Here, we investigated the role of excessive PKR1 signaling in heart.