Relationship between MPV and paraoxonase-1 activity, brachial artery diameter and IMT in patients with diabetes mellitus

Karakaya, Pinar; OKUTURLAR, Yıldız; Mert, Meral; GEDİKBAŞI, ASUMAN; Islim, Filiz; Acarer, Didem; Kocamaz, Nursel; Soyluk, ÖZLEM; AYAZ, TESLİME; Alarslan, Pinar; Harmankaya, Ozlem; Kumbasar, Abdulbaki

doi:10.1080/16089677.2016.1212964

Relationship between MPV and paraoxonase-1 activity, brachial artery diameter and IMT in patients with diabetes mellitus

Karakaya P., OKUTURLAR Y., Mert M., GEDİKBAŞI A., Islim F., Acarer D., ...Daha Fazla

JOURNAL OF ENDOCRINOLOGY METABOLISM AND DIABETES OF SOUTH AFRICA, cilt.21, sa.3, ss.40-46, 2016 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 21 Sayı: 3
Basım Tarihi: 2016
Doi Numarası: 10.1080/16089677.2016.1212964
Dergi Adı: JOURNAL OF ENDOCRINOLOGY METABOLISM AND DIABETES OF SOUTH AFRICA
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE
Sayfa Sayıları: ss.40-46
İstanbul Üniversitesi Adresli: Hayır

Özet

Aims: Higher mean platelet volume (MPV) in diabetic patients has been considered as an emerging risk factor for diabetes related micro-and macrovascular complications. Human paraoxonase 1/arylesterase (PON1), which has antioxidant and antiatherogenic properties, is documented in high oxidative stress conditions like uncontrolled diabetes. The present study aimed to evaluate the relationship between mean platelet volume (MPV) and paraoxonase-1 (PON-1) activity, brachial artery diameter (BAd) and intima media thickness (BA-IMT), in diabetic patients with regard to obesity and diabetic complications.