Akademik Veri Yönetim Sistemi
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases, Barcelona, İspanya, 4 - 07 Mayıs 2023, ss.499
Objective: Osteoporotic fractures are an important cause of morbidity, mortality and loss of functionality in older patients. Recent studies have shown that frailty is an indicator for osteoporotic fractures. It is important to give priority to screening and treatment of osteoporosis in frail patients. In this context, we planned to examine the relationship between two different frailty screening tools and 90-d all-cause mortality in geriatric inpatients.
Methods: Patients aged ≥60 years who admitted to a university hospital geriatrics service between June 2021 and August 2022were included in the study. Demographic characteristics, number and types of diseases, number of drugs, data of geriatric syndromes obtained through the comprehensive geriatric evaluation of the patients were recorded retrospectively from the patient files. The patient’s mortality and length of stay data were obtained through the health ministry system. During their hospitalization, patients were screened with two different frailty scales, the Simpler Modified Fried scale (MFS) and the clinical frailty scale (CFS). Patients with ≥5 on the CFS scale and ≥3 on the MFS scale were evaluated as frail. Malnutrition screening was performed by Mini Nutritional Test -Short Form (MNA-SF). Patients with an MNASF score of 11 were accepted as undernutrition. Polypharmacy was evaluated as the number of drugs4. Functional status of the participants was evaluated with the daily living activities (ADL) the 6-item Katz scale and the instrumental daily living activities (IADL) with the 8-item Lawton Brody scale.
Results: The study included 84 participants a mean age of 78.3±7.6. Participants of 36.9% were male. The prevalence of frailty by CFS and MFS was 60.7%- 89.3% respectively. All-cause mortality within 90 d prevalence was 19%. In univariate analyses using the Kaplan-Meier survival method, the CFS scale was statistically significantly related with 90-d all-cause mortality (p<0.001). However, in univariate analyses, MFS scale was not found to be statistically significant (p:0.849). A statistically significant relation was found between CFS scale and all-cause mortality after adjusting for age, gender, undernutrition, number of diseases, and falls in the evaluation of screening tools in multivariate analysis with Cox regression analysis [(p<0.001), Hazzard Ratio (HR): 3.078; (95%Cl: 1.746-5.425)]. A statistically significant correlation was found between CFS and MFS frailty screening tools (r:0.602, p<0.001).
Conclusion: In the results of this study, in which frailty was evaluated using two different scales in hospitalized older adults, the CFS scale came to the fore in predicting all-cause mortality within 90 d.