Is there any Association between the Functional Variants of the NOS3 Gene and Psoriasis?

Pehlivan S., Inaloz H. S., NURSAL A. F., Gulel A., PEHLİVAN M.

ISTANBUL MEDICAL JOURNAL, vol.19, no.2, pp.152-157, 2018 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.5152/imj.2018.05658
  • Journal Name: ISTANBUL MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.152-157
  • Keywords: Psoriasis, endothelial nitric oxide synthase gene, G894T, VNTR, OXIDE SYNTHASE GENE, NITRIC-OXIDE, OXIDATIVE STRESS, POLYMORPHISM, GLU298ASP, VULGARIS, DISEASE, PLASMA, SKIN
  • Istanbul University Affiliated: Yes

Abstract

Introduction: Psoriasis (Ps) is a chronic, immune-mediated inflammatory skin disorder with an incompletely understood etiology. The aim of this study was to investigate the relationship between the suspectibility to Ps and G894T (rs1799983) and variable number tandem repeat (VNTR) variants of the endothelial nitric oxide synthase (NOS3) gene.