Is there any Association between the Functional Variants of the NOS3 Gene and Psoriasis?

Pehlivan S., Inaloz H. S., NURSAL A. F., Gulel A., PEHLİVAN M.

ISTANBUL MEDICAL JOURNAL, cilt.19, sa.2, ss.152-157, 2018 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.5152/imj.2018.05658
  • Dergi Adı: ISTANBUL MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.152-157
  • Anahtar Kelimeler: Psoriasis, endothelial nitric oxide synthase gene, G894T, VNTR, OXIDE SYNTHASE GENE, NITRIC-OXIDE, OXIDATIVE STRESS, POLYMORPHISM, GLU298ASP, VULGARIS, DISEASE, PLASMA, SKIN
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: Psoriasis (Ps) is a chronic, immune-mediated inflammatory skin disorder with an incompletely understood etiology. The aim of this study was to investigate the relationship between the suspectibility to Ps and G894T (rs1799983) and variable number tandem repeat (VNTR) variants of the endothelial nitric oxide synthase (NOS3) gene.