Risk Factors and Time to Clinical Symptoms of Multiple Sclerosis Among Patients With Radiologically Isolated Syndrome

Lebrun-Frenay C., Rollot F., Mondot L., Zephir H., Louapre C., Le Page E., ...More

JAMA NETWORK OPEN, vol.4, no.10, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 10
  • Publication Date: 2021
  • Doi Number: 10.1001/jamanetworkopen.2021.28271
  • Journal Name: JAMA NETWORK OPEN
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Istanbul University Affiliated: Yes

Abstract

IMPORTANCE Younger age, oligoclonal bands, and infratentorial and spinal cord lesions are factors associated with an increased 10-year risk of clinical conversion from radiologically isolated syndrome (RIS) to multiple sclerosis (MS). Whether disease-modifying therapy is beneficial for individuals with RIS is currently unknown.