Early Induction of ADAMTS1,-4,-5 and-9 in IL-Stimulated Mouse Astrocytes

Abali, Osman; Gokce, Emre; Cemil, Berker; Erdogan, Bulent; Yonezawa, Tomoko; Demircan, Kadir

doi:10.5137/1019-5149.jtn.9043-13.2

Early Induction of ADAMTS1,-4,-5 and-9 in IL-Stimulated Mouse Astrocytes

Abali O., Gokce E. C., Cemil B., Erdogan B., Yonezawa T., Demircan K.

TURKISH NEUROSURGERY, vol.24, no.4, pp.519-524, 2014 (SCI-Expanded, Scopus, TRDizin)

Publication Type: Article / Article
Volume: 24 Issue: 4
Publication Date: 2014
Doi Number: 10.5137/1019-5149.jtn.9043-13.2
Journal Name: TURKISH NEUROSURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.519-524
Istanbul University Affiliated: Yes

Abstract

AIM: Astrocytes and extracellular matrix molecules have important roles in regulating synaptic functions between neurons in the central nervous system. However, under pathological conditions, these constituents are activated to form glial scar that is thought to be harmful for neuronal regeneration. The aim of this study was to evaluate the expression pattern of ADAMTS1, -4, -5 and -9 in IL-1 stimulated astrocyte cultures obtained from postnatal day zero mouse brains.