Early Induction of ADAMTS1,-4,-5 and-9 in IL-Stimulated Mouse Astrocytes


Abali O., Gokce E. C. , Cemil B., Erdogan B., Yonezawa T., Demircan K.

TURKISH NEUROSURGERY, cilt.24, ss.519-524, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 24 Konu: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5137/1019-5149.jtn.9043-13.2
  • Dergi Adı: TURKISH NEUROSURGERY
  • Sayfa Sayıları: ss.519-524

Özet

AIM: Astrocytes and extracellular matrix molecules have important roles in regulating synaptic functions between neurons in the central nervous system. However, under pathological conditions, these constituents are activated to form glial scar that is thought to be harmful for neuronal regeneration. The aim of this study was to evaluate the expression pattern of ADAMTS1, -4, -5 and -9 in IL-1 stimulated astrocyte cultures obtained from postnatal day zero mouse brains.