Early Induction of ADAMTS1,-4,-5 and-9 in IL-Stimulated Mouse Astrocytes

Abali O., Gokce E. C., Cemil B., Erdogan B., Yonezawa T., Demircan K.

TURKISH NEUROSURGERY, cilt.24, sa.4, ss.519-524, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5137/1019-5149.jtn.9043-13.2
  • Dergi Adı: TURKISH NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.519-524
  • İstanbul Üniversitesi Adresli: Evet

Özet

AIM: Astrocytes and extracellular matrix molecules have important roles in regulating synaptic functions between neurons in the central nervous system. However, under pathological conditions, these constituents are activated to form glial scar that is thought to be harmful for neuronal regeneration. The aim of this study was to evaluate the expression pattern of ADAMTS1, -4, -5 and -9 in IL-1 stimulated astrocyte cultures obtained from postnatal day zero mouse brains.