The Effect of Suppressed Levels of Uninvolved Immunoglobulins on the Prognosis of Symptomatic Multiple Myeloma.


Sari M., Sari S., Nalcaci M.

Turkish journal of haematology : official journal of Turkish Society of Haematology, cilt.34, sa.2, ss.131-136, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/tjh.2016.0161
  • Dergi Adı: Turkish journal of haematology : official journal of Turkish Society of Haematology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.131-136
  • Anahtar Kelimeler: Multiple myeloma, Prognostic factors, Serum immunoglobulins, Nephelometric measurement, M-protein, CRITERIA
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: The majority of multiple myeloma (MM) patients have high levels of monoclonal immunoglobulin in the serum and/or urine and suppressed levels of the uninvolved immunoglobulins. The prognostic significance of this phenomenon has not been assessed sufficiently. In this study, our aim is to evaluate the prognostic significance of uninvolved immunoglobulin suppression measured by nephelometry in patients with new symptomatic MM and the association with other features of the disease.