Biological evaluation of stachys iberica subsp. stenostachya (boiss.) rech.f. And scutellaria orientalis subsp. sosnowskyi (takht.) fed. growing in eastern anatolia

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Toplan G. G., Civas A., KARA M. T., TAŞKIN T., Genc G. E.

International Journal of Secondary Metabolite, vol.8, no.4, pp.364-375, 2021 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.21448/ijsm.979820
  • Journal Name: International Journal of Secondary Metabolite
  • Journal Indexes: Scopus, Central & Eastern European Academic Source (CEEAS), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.364-375
  • Keywords: Acetylcholinesterase, Antimicrobial, Antioxidant, Lamiaceae, Turkey
  • Istanbul University Affiliated: Yes


© 2021 International Journal of Secondary Metabolite. All rights reserved.Lamiaceae is one of the largest families in the plant kingdom, including the genus Stachys and Scutellaria, which are used in many folk medicines throughout the world for the prevention and also the treatment of several disorders. In vitro biological potential of Stachys iberica subsp. stenostachya and Scutellaria orientalis subsp. sosnowskyi were investigated in the current study. The aerial parts of the plants were extracted using different solvents such as n-hexane, chloroform, and methanol. In addition, infusions of each plant were prepared. The antioxidant potential of the samples was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), ABTS assays, ferrous ion-chelating, and ferric reducing antioxidant power (FRAP) assays. Anticholinesterase activity of the extracts was also determined. Spectrophotometric analysis was used to assess the total phenolic content of the samples. The antimicrobial activities of samples were determined by minimal inhibitory concentration (MIC) against seven bacteria and three Candida spp. yeast. According to the findings, the infusion demonstrated significant antioxidant properties, whilst the extracts demonstrated high-to-moderate antioxidant effects. The n-hexane extracts showed higher antifungal activity against C.parapsilosis and C.tropicalis. These outcomes suggest that these two species from Turkey could be employed in the manufacture of phytopharmaceuticals.