A case-control study on effects of the ATM, RAD51 and TP73 genetic variants on colorectal cancer risk

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Atıf İçin Kopyala

Yazici M., Yilmaz U., Yilmaz N., Celik F., Isikoren E. G., Celikel B., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.44, sa.6, ss.778-786, 2019 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 44 Sayı: 6
• Basım Tarihi: 2019
• Doi Numarası: 10.1515/tjb-2019-0222
• Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.778-786
• İstanbul Üniversitesi Adresli: Evet

Özet

Aim: ATM, RAD51 and TP73 are genes that take part in DNA repair pathways. The aim of this prospective case-control study was to determine the genotype and allele distributions of the ATM 5'-UTR G/A, RAD51 135 G/C and TP73 GC/AT polymorphisms and their relationship with clinical parameters in Turkish colorectal cancer (CRC) patients.