Evaluation of obstetric outcomes and prognostic significance of graft function in kidney transplant recipient pregnancies


MADAZLI R., KAYMAK D., Alpay V., Erenel H. , DİNCER M. T. , SEYAHİ N.

HYPERTENSION IN PREGNANCY, cilt.39, ss.89-94, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 39 Konu: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1080/10641955.2020.1727498
  • Dergi Adı: HYPERTENSION IN PREGNANCY
  • Sayfa Sayıları: ss.89-94

Özet

Objective: To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation. Methods: We retrospectively reviewed 32 singleton pregnancies in kidney transplant recipients. Obstetric outcomes were explored according to the estimated glomerular filtration rates (eGFR) of patients. Results: The incidences of fetal growth restriction, preeclampsia were 18.8% and 34.4%, respectively. There was a significant negative correlation between first-trimester eGFR and perinatal mortality (r = -0.546, p = .0.001) and composite adverse obstetric outcome (r = -0.415, p = .0.018). Conclusion: The degree of transplanted kidney function impairment at the beginning of pregnancy is the major determinant of pregnancy outcome.