Evaluation of obstetric outcomes and prognostic significance of graft function in kidney transplant recipient pregnancies

MADAZLI R., KAYMAK D., Alpay V., Erenel H., DİNCER M. T., SEYAHİ N.

HYPERTENSION IN PREGNANCY, cilt.39, sa.2, ss.89-94, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1080/10641955.2020.1727498
  • Dergi Adı: HYPERTENSION IN PREGNANCY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.89-94
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation. Methods: We retrospectively reviewed 32 singleton pregnancies in kidney transplant recipients. Obstetric outcomes were explored according to the estimated glomerular filtration rates (eGFR) of patients. Results: The incidences of fetal growth restriction, preeclampsia were 18.8% and 34.4%, respectively. There was a significant negative correlation between first-trimester eGFR and perinatal mortality (r = -0.546, p = .0.001) and composite adverse obstetric outcome (r = -0.415, p = .0.018). Conclusion: The degree of transplanted kidney function impairment at the beginning of pregnancy is the major determinant of pregnancy outcome.