AR-A014418 as a glycogen synthase kinase-3 inhibitor: Anti-apoptotic and therapeutic potential in experimental spinal cord injury

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Tuncdemir M., YILDIRIM A., Karaoglan A., AKDEMİR O., Ozturk M.

NEUROCIRUGIA, vol.24, no.1, pp.22-32, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 24 Issue: 1
• Publication Date: 2013
• Doi Number: 10.1016/j.neucir.2011.12.006
• Journal Name: NEUROCIRUGIA
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.22-32
• Istanbul University Affiliated: Yes

Abstract

Objectives: We aimed to investigate the effects of AR-A014418, a strong inhibitor specific to GSK-3beta, on neuronal apoptosis and neuroprotection in the traumatic SCI model.