Lipoid proteinosis of the larynx


Oz F., Kalekoglu N., Karakullukcu B., Ozturk O. , Oz B.

JOURNAL OF LARYNGOLOGY AND OTOLOGY, cilt.116, ss.736-739, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 116 Konu: 9
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1258/002221502760238082
  • Dergi Adı: JOURNAL OF LARYNGOLOGY AND OTOLOGY
  • Sayfa Sayıları: ss.736-739

Özet

Lipoid proteinosis is a rare disease that presents with hyaline deposits in many tissues. It involves predominantly the skin and upper aerodigestive tract, presenting with small yellowish papules and hoarseness. It may involve the central nervous system and cause intracerebral calcifications. Laryngeal lesions may resemble singer's nodule or chronic laryngitis. The pathogenesis of the disease is not clear although several studies suggest a defective collagen production and/or lysosomal storage disease. In this article two cases with skin and larynx involvement are reported.