Gender- and obesity-specific effect of apolipoprotein C3 gene (APOC3)-482C > T polymorphism on triglyceride concentration in Turkish adults


Coban N., Onat A., Guclu-Geyik F., Komurcu-Bayrak E., Sansoy V., HERGENÇ G., ...More

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol.50, no.2, pp.285-292, 2012 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 50 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1515/cclm.2011.747
  • Journal Name: CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.285-292
  • Keywords: apolipoprotein C3-482C > T polymorphism, fasting triglyceride, gender difference, obesity, Turkish population, METABOLIC SYNDROME, LIPOPROTEIN METABOLISM, CARDIOVASCULAR-DISEASE, INSULIN-RESISTANCE, ABDOMINAL OBESITY, APOC3 GENE, RISK, VARIANTS, ASSOCIATION, GLUCOSE
  • Istanbul University Affiliated: Yes

Abstract

Background: Apolipoprotein C3 (APOC3) gene polymorphisms are associated with cardiometabolic risk factors, varying in ethnicities. This study aimed to investigate such association between the APOC3 -482C>T polymorphism and cardiometabolic risk factors in the turkish adult risk factor (TARF) study cohort, stratifying by gender and obesity.