Vascular endothelial growth factor-2578 A/C,-460 T/C and+405 G/C polymorphisms in polycystic ovary syndrome

Vural, Pervin; Kusku-Kiraz, Zeynep; Dogru-Abbasoglu, Semra; CIL, Esra; KARADAG, Berrin; Akgul, Cemil; Uysal, Muejdat

doi:10.1016/j.ejogrb.2009.06.026

Vascular endothelial growth factor-2578 A/C,-460 T/C and+405 G/C polymorphisms in polycystic ovary syndrome

Vural P., Kusku-Kiraz Z., Dogru-Abbasoglu S., CIL E., KARADAG B., Akgul C., ...Daha Fazla

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, cilt.147, sa.1, ss.57-60, 2009 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 147 Sayı: 1
Basım Tarihi: 2009
Doi Numarası: 10.1016/j.ejogrb.2009.06.026
Dergi Adı: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.57-60
Anahtar Kelimeler: Polycystic ovary syndrome, Vascular endothelial growth factor, Polymorphism, FACTOR GENE POLYMORPHISMS, STROMAL BLOOD-FLOW, PERMEABILITY FACTOR, HYPERSTIMULATION SYNDROME, VEGF GENE, ASSOCIATION, WOMEN, SUSCEPTIBILITY, EXPRESSION, GRANULOSA
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Vascular endothelial growth factor (VEGF) may be involved in the physiological regulation of ovarian angiogenesis and pathogenesis of polycystic ovary syndrome (PCOS). VEGF -2578 A/C, -460 T/C and +405 G/C single nucleotide polymorphisms (SNPs) are known to be related to VEGF production.