Effects of Polymorphisms in Interferon lambda 3 (Interleukin 28B) on Sustained Virologic Response to Therapy in Patients With Chronic Hepatitis D Virus Infection

Yilmaz, Emre; Baran, Bülent; Soyer, Ozlem; Onel, Mustafa; Onel, Derya; Ormeci, ASLI; Gokturk, Suut; Evirgen, Sami; Akyuz, Filiz; Demir, Kadir; Besisik, Selman; Kaymakoglu, Sabahattin; Karaca, Cetin

doi:10.1016/j.cgh.2014.01.043

Effects of Polymorphisms in Interferon lambda 3 (Interleukin 28B) on Sustained Virologic Response to Therapy in Patients With Chronic Hepatitis D Virus Infection

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Yilmaz E., Baran B., Soyer O. M., Onel M., Onel D., Ormeci A., ...More

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, vol.12, no.10, pp.1753-1758, 2014 (SCI-Expanded)

Publication Type: Article / Article
Volume: 12 Issue: 10
Publication Date: 2014
Doi Number: 10.1016/j.cgh.2014.01.043
Journal Name: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1753-1758
Keywords: Chronic Delta Hepatitis, SNP, Interferon Lambda 3, Immune Regulation, DELTA-HEPATITIS, HDV INFECTION, CIRRHOSIS, IL28B, ALPHA, TURKEY
Istanbul University Affiliated: Yes

Abstract

BACKGROUND & AIMS: We investigated the association between interferon lambda 3 (IFNL3) genotype (also known as interleukin 28B) and response to IFN alpha therapy in patients with chronic hepatitis D virus (HDV) infection.