MRI in subacute sclerosing panencephalitis

Tuncay R., AkmanDemir G., Gokyigit A., Eraksoy M., Barlas M., Tolun R., ...More

NEURORADIOLOGY, vol.38, no.7, pp.636-640, 1996 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 7
  • Publication Date: 1996
  • Doi Number: 10.1007/s002340050323
  • Title of Journal : NEURORADIOLOGY
  • Page Numbers: pp.636-640


Subacute sclerosing panencephalitis (SSPE) is a progressive, slow virus infection of the brain, caused by the measles virus, attacking children and young adults, We investigated 15 patients with SSPE by MRI, with 5 normal and 10 pathological results. In the early period, lesions were in the grey matter and subcortical white matter. They were asymmetrical and had a predilection for the posterior parts of the hemispheres. Later, high-signal changes in deep white matter and severe cerebral atrophy were observed, Parenchymal lesions significantly correlated with the duration of disease. A significant relationship between MRI findings and clinical stage was observed in the 1st year of the disease.