Effects of sodium hyaluronate and methylprednisolone alone or in combination in preventing epidural fibrosis.
Neurological research, vol.35, no.8, pp.851-6, 2013 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 35 Issue: 8
- Publication Date: 2013
- Doi Number: 10.1179/1743132813y.0000000219
- Journal Name: Neurological research
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.851-6
- Istanbul University Affiliated: Yes
Abstract
Objective: Epidural fibrosis and leptomeningeal adhesion formation are common causes of failed back surgery syndrome (FBSS). We employed a rat model of lumbar laminectomy to evaluate the histopathological effects of sodium hyaluronate (HA) and methylprednisolone (MP) alone or in combination on post-laminectomy epidural fibrosis.