Effects of sodium hyaluronate and methylprednisolone alone or in combination in preventing epidural fibrosis.

Shaban, Madhat; Aras, YAVUZ; Aydoseli, AYDIN; Akcakaya, Mehmet; Sencer, ALTAY; Bayindir, Cicek; Izgi, Ali

doi:10.1179/1743132813y.0000000219

Effects of sodium hyaluronate and methylprednisolone alone or in combination in preventing epidural fibrosis.

Shaban M., Aras Y., Aydoseli A., Akcakaya M. O., Sencer A., Bayindir C., ...Daha Fazla

Neurological research, cilt.35, sa.8, ss.851-6, 2013 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 35 Sayı: 8
Basım Tarihi: 2013
Doi Numarası: 10.1179/1743132813y.0000000219
Dergi Adı: Neurological research
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.851-6
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Epidural fibrosis and leptomeningeal adhesion formation are common causes of failed back surgery syndrome (FBSS). We employed a rat model of lumbar laminectomy to evaluate the histopathological effects of sodium hyaluronate (HA) and methylprednisolone (MP) alone or in combination on post-laminectomy epidural fibrosis.