Effects of sodium hyaluronate and methylprednisolone alone or in combination in preventing epidural fibrosis.

Shaban M., Aras Y., Aydoseli A., Akcakaya M. O., Sencer A., Bayindir C., ...Daha Fazla

Neurological research, cilt.35, sa.8, ss.851-6, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 8
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1179/1743132813y.0000000219
  • Dergi Adı: Neurological research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.851-6
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Epidural fibrosis and leptomeningeal adhesion formation are common causes of failed back surgery syndrome (FBSS). We employed a rat model of lumbar laminectomy to evaluate the histopathological effects of sodium hyaluronate (HA) and methylprednisolone (MP) alone or in combination on post-laminectomy epidural fibrosis.