Effects of sodium hyaluronate and methylprednisolone alone or in combination in preventing epidural fibrosis


Shaban M., Aras Y. , Aydoseli A. , Akcakaya M. O. , Sencer A. , Bayindir C., ...Daha Fazla

NEUROLOGICAL RESEARCH, cilt.35, ss.851-856, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 35 Konu: 8
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1179/1743132813y.0000000219
  • Dergi Adı: NEUROLOGICAL RESEARCH
  • Sayfa Sayıları: ss.851-856

Özet

Objective: Epidural fibrosis and leptomeningeal adhesion formation are common causes of failed back surgery syndrome (FBSS). We employed a rat model of lumbar laminectomy to evaluate the histopathological effects of sodium hyaluronate (HA) and methylprednisolone (MP) alone or in combination on post-laminectomy epidural fibrosis.