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Telli P., Ozturk N. B., Hakan M. T., Cavus B., Ormeci A. C., Yakut A., ...More
HEPATOLOGY FORUM, vol.3, no.3, pp.77-81, 2022 (ESCI)
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Publication Type:
Article / Article
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Volume:
3
Issue:
3
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Publication Date:
2022
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Doi Number:
10.14744/hf.2022.2022.0021
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Journal Name:
HEPATOLOGY FORUM
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Journal Indexes:
Emerging Sources Citation Index (ESCI)
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Page Numbers:
pp.77-81
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Keywords:
Cirrhosis, hepatitis B virus, hepatocellular carcinoma, CIRCULATING NUCLEIC-ACIDS, DNA METHYLATION, CANCER, BIOMARKERS, CPG
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Istanbul University Affiliated:
Yes
Abstract
Background and Aim: Chronic hepatitis B virus (HBV) infection is a major cause of hepatocellular carcinoma (HCC). Circulating cell-free DNA (cfDNA) methylation of tumor suppressor genes are emerging potential biomarkers in HCC. We aimed to evaluate the cfDNA methylation status of RASSF1 and CDKN2AIP genes in patients with liver cirrhosis (LC) with or without HCC caused by HBV.