Case report: POEMS syndrome in childhood
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, vol.30, no.3, pp.235-238, 2008 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 30 Issue: 3
- Publication Date: 2008
- Doi Number: 10.1097/mph.0b013e31815f88da
- Journal Name: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.235-238
- Istanbul University Affiliated: Yes
Abstract
POEMS syndrome is a rare multisystem disorder, which is characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. We report a 15-year-old girl with POEMS syndrome, who developed growth retardation, delayed puberty, gradually increasing abdominal distention, brown skin pigmentation, hypogonadism, hepatosplenomegaly, lympadenomegaly, monoclonal gammopathy, and anemia. The patient dramatically responded to pulse steroid therapy. To our knowledge, this patient is one of the youngest reported cases of POEMS syndrome.