Evaluation of lipid peroxidation, oxidant/antioxidant status, and serum nitric oxide levels in alopecia areata

Koca R., ARMUTCU F., Altinyazar C., Gurel A.

MEDICAL SCIENCE MONITOR, vol.11, no.6, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 6
  • Publication Date: 2005
  • Journal Name: MEDICAL SCIENCE MONITOR
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Istanbul University Affiliated: Yes

Abstract

Background: The pathophysiology of alopecia areata (AA) has not been clearly defined; however, it appears as a tissue-restricted autoimmunne disease mediated by T lymphocytes. Immunohistochemical studies have shown peri- and infra-follicular inflammatory infiltrate which damages hair follicles. We. analyzed the role of lipid peroxidation and oxidant-antioxidant enzymes in the pathogenesis of AA.