CHARACTERIZATION AND ISOLATION OF VERY SMALL EMBRYONIC-LIKE (VSEL) STEM CELLS OBTAINED FROM HUMAN PERIPHERAL BLOOD


Erdem Kuruca S. , Celik D. D. , Demirel G., Ozerkan D.

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, vol.82, no.2, pp.96-106, 2019 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 82 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.26650/iuitfd.2018.0001
  • Journal Name: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
  • Journal Indexes: Emerging Sources Citation Index, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.96-106

Abstract

Objective: Stem cell transplantation is considered to be one of the available treatments for malign or hereditary blood diseases and bone marrow failure. Peripheral blood progenitor cells (PBPC) are widely used for this technique. Recently a new type of stem cell with a pluripotent potential has been identified. These cells, called very small embryonic-like (VSEL) stem cells, are thought to be found in peripheral blood (PB) in adult individuals. The aim of this study was to obtain and identify VSEL stem cells using a peripheral blood source.