Standardized uptake values of normal organs on F-18-fluorodeoxyglucose positron emission tomography and computed tomography imaging

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Zincirkeser S., Sahin E., Halac M., Sager S.

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, vol.35, no.2, pp.231-236, 2007 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 35 Issue: 2
• Publication Date: 2007
• Doi Number: 10.1177/147323000703500207
• Journal Name: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.231-236
• Istanbul University Affiliated: No

Abstract

Standardized uptake values (SUVs) of normal organs were evaluated by F-18-fluorodeoxyglucose (18F-FDG) positron emission tomography and computed tomography (PET-CT) scanning. Seventy patients (38 men and 32 women) with no non-physiological 18F-FDG uptake participated in the study. All patients fasted for at least 4 h before PET-CT imaging and their fasting blood glucose levels were within the normal range. Image acquisition was performed after intravenous administration of 18F-FDG and images were obtained from the vertex to the upper thigh region. The SUVs of various organs were determined from the transverse views. The uptake of 18F-FDG was highest in the cerebrum, cerebellum, myocardium, tonsils, liver and spleen in both sexes. Having knowledge of the physiological uptake of 18F-FDG and normal organ SUVs is required for the correct interpretation of whole-body 18F-FDG-PET-CT studies.