Neuroprotective and memory-enhancing effects of methanolic leaf extract of Peristrophe bicalyculata in rat model of type 2 diabetes mellitus.

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Njan A. A., Adenuga F. O., Ajayi A. M., Sotunde O., Ologe M. O., Olaoye S. O., ...More

Heliyon, vol.6, no.5, 2020 (SCI-Expanded, ESCI, Scopus)

• Publication Type: Article / Article
• Volume: 6 Issue: 5
• Publication Date: 2020
• Doi Number: 10.1016/j.heliyon.2020.e04011
• Journal Name: Heliyon
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Emerging Sources Citation Index (ESCI), Scopus, CAB Abstracts, Veterinary Science Database, Directory of Open Access Journals
• Keywords: Diabetes mellitus, Peristrophe bicalyculata, Neuroprotection, Pioglitazone, Oxidative stress, Endocrinology, Diabetes, Health sciences, Alternative medicine, Pharmaceutical science, Natural product chemistry, Physiology, TOCOTRIENOL, NECROSIS, STRESS, OXIDE, ASSAY
• Istanbul University Affiliated: Yes

Abstract

This study investigated the effect of methanolic leaf extract of Peristrophe Bicalyculata (MEPb) on type 2 diabetes mellitus (T2DM) associated cognitive decline in Wistar rats.