Role of mast cells and their mediators in failing myocardium under mechanical ventricular support

Akgul, Ahmet; SKRABAL, CA; THOMPSON, LO; LOEBE, M; LAFUENTE, JA; NOON, GP; YOUKER, KA

doi:10.1016/j.healun.2003.06.006

Role of mast cells and their mediators in failing myocardium under mechanical ventricular support

Atıf İçin Kopyala

Akgul A., SKRABAL C., THOMPSON L., LOEBE M., LAFUENTE J., NOON G., ...Daha Fazla

JOURNAL OF HEART AND LUNG TRANSPLANTATION, cilt.23, sa.6, ss.709-715, 2004 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 23 Sayı: 6
Basım Tarihi: 2004
Doi Numarası: 10.1016/j.healun.2003.06.006
Dergi Adı: JOURNAL OF HEART AND LUNG TRANSPLANTATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.709-715
İstanbul Üniversitesi Adresli: Hayır

Özet

Background: Mast cells have been implicated in tissue remodeling and fibroblast stimulation. We explored the effect of mechanical support by left ventricular assist device (LVAD) in failing myocardium and looked into grade and distribution of interstitial fibrosis, mast cell density, mast cell phenotypes and basic fibroblast growth factor (bFGF) expression pre- and post-LVAD.