Positive outcomes of phosphodiesterase type 5 inhibitor on histopathologic and biochemical changes induced by ureteral obstruction

Kokturk S., Benli E., Ayyildiz A., Cirrik S., Cetinkol Y., Ayyildiz S. N., ...Daha Fazla

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, cilt.65, sa.3, ss.388-393, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1590/1806-9282.65.3.388
  • Dergi Adı: REVISTA DA ASSOCIACAO MEDICA BRASILEIRA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.388-393
  • Anahtar Kelimeler: Phosphodiesterase type 5 inhibitor, Tadalafil, obstruction, histopathologic and biochemical, TRANSFORMING-GROWTH-FACTOR, TADALAFIL, FIBROSIS, RATS, TRANSITION, APOPTOSIS, DISEASE, INJURY, DAMAGE
  • İstanbul Üniversitesi Adresli: Evet

Özet

OBJECTIVES: We examined the effects of tadalafil, one of the phosphodiesterase type 5 (PDE5) inhibitors, in a rat model of with partial and complete unilateral ureteral obstruction (UUO).