Nitrotyrosine formation and heme oxygenase-1 expression in endotoxemic cirrhotic rats


Dogru-Abbasoglu S. , PARILDAR-KARPUZOGLU H., BALKAN J., AYKAC-TOKER G., UYSAL M.

ARCHIVES OF MEDICAL RESEARCH, cilt.38, ss.28-33, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 38 Konu: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.arcmed.2006.07.003
  • Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
  • Sayfa Sayıları: ss.28-33

Özet

Background. Endotoxemia increases hepatic toxicity and mortality in cirrhosis. Because the mechanism of augmented hepatotoxicity in endotoxemic cirrhotic rats is still unclear, we wanted to investigate whether oxidative and nitrosative stress play a causative role in lipopolysaccharide (LPS)-treated cirrhotic rats.