SYNTHESIS AND ANTIOXIDANT ACTIVITY OF NOVEL 8-FORMYL-4-SUBSTITUED COUMARINS


Onar H. C. , Vardar B. A.

BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA, vol.32, no.1, pp.175-178, 2018 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.4314/bcse.v32i1.17
  • Title of Journal : BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA
  • Page Numbers: pp.175-178

Abstract

4-Methyl-8-formyl- and 4-phenyl-8-formyl coumarins have been synthesized by Pechmann reaction using oxalic acid catalyst for the first time. 4-Propyl-7-hydroxy-, and 4-methyl-7-methoxy coumarins have also been accomplished by this catalyst for the first time. They have been characterizated by IR, H-1-NMR, C-13-NMR, mass and elemental analysis. Furthermore, the obtained coumarins were compared according to antioxidant activity by DPPH method.