Effect of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier permeability and brain edema after experimental traumatic diffuse brain injury

Imer M., Omay B., Uzunkol A., Erdem T., Sabanci P. A., Karasu A., ...Daha Fazla

NEUROLOGICAL RESEARCH, cilt.31, sa.9, ss.977-981, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 9
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1179/174313209x385617
  • Dergi Adı: NEUROLOGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.977-981
  • Anahtar Kelimeler: Diffuse brain injury, blood-brain barrier, brain edema, magnesium, MK-801, FOCAL CEREBRAL-ISCHEMIA, EXPERIMENTAL HEAD TRAUMA, ACUTE SUBDURAL-HEMATOMA, D-ASPARTATE ANTAGONISTS, RATS, THERAPY, INFARCTION, SULFATE, MODEL, REDUCTION
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Glutamate antagonists are very attractive drugs in laboratory works to protect neural tissue against ischemia. In this work, the effects of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier (BBB) and brain edema after experimentally induced traumatic brain injury are evaluated.