SERUM BIOMARKERS IN PATIENTS WITH STABLE AND ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A COMPARATIVE STUDY

Sahin F., Kosar A. F., Aslan A. F., ARPINAR YİĞİTBAŞ B., Uslu B.

JOURNAL OF MEDICAL BIOCHEMISTRY, cilt.38, sa.4, ss.503-511, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.2478/jomb-2018-0050
  • Dergi Adı: JOURNAL OF MEDICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.503-511
  • Anahtar Kelimeler: COPD, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, inflammatory biomarkers, TO-LYMPHOCYTE RATIO, C-REACTIVE PROTEIN, MEAN PLATELET VOLUME, INFLAMMATORY BIOMARKERS, SYSTEMIC INFLAMMATION, NEUTROPHIL, COPD, COMORBIDITIES, ASSOCIATION, ICU
  • İstanbul Üniversitesi Adresli: Hayır

Özet

Background: Mean platelet volume (MPV), neutrophil-tolymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have all been investigated as novel inflammatory markers of cardiac and oncological diseases, while there is only a limited number of studies investigating these markers in chronic obstructive pulmonary disease (COPD). In the present study we examine NLR, PLR; and other markers, such as eosinophil, MPV, plateletcrit (PCT), platelet distribution width (PDW), red cell distribution width (RDW), and C-reactive protein (CRP) in patients with stable and acute exacerbation of COPD.