SERUM BIOMARKERS IN PATIENTS WITH STABLE AND ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A COMPARATIVE STUDY

Sahin F., Kosar A. F., Aslan A. F., ARPINAR YİĞİTBAŞ B., Uslu B.

JOURNAL OF MEDICAL BIOCHEMISTRY, vol.38, no.4, pp.503-511, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.2478/jomb-2018-0050
  • Journal Name: JOURNAL OF MEDICAL BIOCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.503-511
  • Keywords: COPD, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, inflammatory biomarkers, TO-LYMPHOCYTE RATIO, C-REACTIVE PROTEIN, MEAN PLATELET VOLUME, INFLAMMATORY BIOMARKERS, SYSTEMIC INFLAMMATION, NEUTROPHIL, COPD, COMORBIDITIES, ASSOCIATION, ICU
  • Istanbul University Affiliated: No

Abstract

Background: Mean platelet volume (MPV), neutrophil-tolymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have all been investigated as novel inflammatory markers of cardiac and oncological diseases, while there is only a limited number of studies investigating these markers in chronic obstructive pulmonary disease (COPD). In the present study we examine NLR, PLR; and other markers, such as eosinophil, MPV, plateletcrit (PCT), platelet distribution width (PDW), red cell distribution width (RDW), and C-reactive protein (CRP) in patients with stable and acute exacerbation of COPD.