CHEMICALLY INDUCED OXIDATIVE STRESS DECREASES HOMOLOGOUS RECOMBINATION RATE AND REC12 GENE EXPRESSION IN THE FISSION YEAST

Yilmaz D., Yilmazer M., Tumkaya T., Karaer Uzuner S.

FRESENIUS ENVIRONMENTAL BULLETIN, cilt.27, sa.7, ss.4995-5000, 2018 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 7
  • Basım Tarihi: 2018
  • Dergi Adı: FRESENIUS ENVIRONMENTAL BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.4995-5000
  • İstanbul Üniversitesi Adresli: Evet

Özet

Homologous recombination plays an important role in maintaining the genome stability of prokaryotic and eukaryotic organisms. In this study, rec12 gene expression and alterations in homologous recombination frequency were investigated under H2O2 and CuSO4 induced oxidative stress in the unicellular, eukaryotic model organism, Schizosaccharomyces pombe.