National Early Warning Score 2 and laboratory predictors correlate with clinical deterioration in hospitalized patients with COVID-19

Tuncer G., Surme S., Bayramlar O. F., Karanalbant H. K., Copur B., Yazla M., ...More

BIOMARKERS IN MEDICINE, vol.15, pp.807-820, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15
  • Publication Date: 2021
  • Doi Number: 10.2217/bmm-2021-0061
  • Journal Name: BIOMARKERS IN MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.807-820
  • Istanbul University Affiliated: Yes

Abstract

Aim: We aimed to determine the prognostic values of the National Early Warning Score 2 (NEWS2) and laboratory parameters during the first week of COVID-19. Materials & methods: All adult patients who were hospitalized for confirmed COVID-19 between 11 March and 11 May 2020 were retrospectively included. Results: Overall, 611 patients were included. Our results showed that NEWS2, procalcitonin, neutrophil/lymphocyte ratio and albumin at D0, D3, D5 and D7 were the best predictors for clinical deterioration defined as a composite of ICU admission during hospitalization or in-hospital death. Procalcitonin had the highest odds ratio for clinical deterioration on all days. Conclusion: This study provides a list of several laboratory parameters correlated with NEWS2 and potential predictors for clinical deterioration in patients with COVID-19.