Reduced Akkermansia muciniphila and Faecalibacterium prausnitzii levels in the gut microbiota of children with allergic asthma


Demirci M., Tokman H. B., Uysal H., Demiryas S., Karakullukcu A., Saribas S., ...More

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, vol.47, no.4, pp.365-371, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.1016/j.aller.2018.12.009
  • Journal Name: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.365-371
  • Keywords: Asthmatic children, Akkermansia muciniphila, Faecalibacterium prausnitzii, Hygiene hypothesis, qPCR, ATOPIC-DERMATITIS, FOOD ALLERGY, ASSOCIATION, DIVERSITY, BACTERIA, DISEASE
  • Istanbul University Affiliated: Yes

Abstract

Introduction and objectives: The amounts of Akkermansia muciniphila and Faecalibacterium prausnitzii in gut microbiota are reduced in patients with allergic diseases compared to healthy controls. We aimed to quantify levels of A. muciniphila and F. prausnitzii amounts using real-time quantitative PCR (qPCR) in the gut microbiota of children with allergic asthma and in healthy controls.