Reduced Akkermansia muciniphila and Faecalibacterium prausnitzii levels in the gut microbiota of children with allergic asthma

Demirci, M.; Tokman, H.; Uysal, Hayriye; Demiryas, S.; Karakullukcu, A.; Saribas, Abdulkerim; Cokugras, H.; Kocazeybek, B.

doi:10.1016/j.aller.2018.12.009

Reduced Akkermansia muciniphila and Faecalibacterium prausnitzii levels in the gut microbiota of children with allergic asthma

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Demirci M., Tokman H. B., Uysal H., Demiryas S., Karakullukcu A., Saribas S., ...More

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, vol.47, no.4, pp.365-371, 2019 (SCI-Expanded)

Publication Type: Article / Article
Volume: 47 Issue: 4
Publication Date: 2019
Doi Number: 10.1016/j.aller.2018.12.009
Journal Name: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.365-371
Keywords: Asthmatic children, Akkermansia muciniphila, Faecalibacterium prausnitzii, Hygiene hypothesis, qPCR, ATOPIC-DERMATITIS, FOOD ALLERGY, ASSOCIATION, DIVERSITY, BACTERIA, DISEASE
Istanbul University Affiliated: Yes

Abstract

Introduction and objectives: The amounts of Akkermansia muciniphila and Faecalibacterium prausnitzii in gut microbiota are reduced in patients with allergic diseases compared to healthy controls. We aimed to quantify levels of A. muciniphila and F. prausnitzii amounts using real-time quantitative PCR (qPCR) in the gut microbiota of children with allergic asthma and in healthy controls.