Effects of Tianeptine Pretreatment on Stress-Induced Trace Element Alterations in Rats

Karakoc, Yunus; KASAR, Muzaffer; Mengi, Murat; YILDIRIM, Ejder; Yurdakos, Ertan; Barutcu, Ümit

Effects of Tianeptine Pretreatment on Stress-Induced Trace Element Alterations in Rats

Karakoc Y., KASAR M., Mengi M., YILDIRIM E. A., Yurdakos E., Barutcu U. B.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, vol.19, 2009 (SCI-Expanded, TRDizin)

Publication Type: Article / Article
Volume: 19
Publication Date: 2009
Journal Name: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
Istanbul University Affiliated: Yes

Abstract

Introduction: Although the alterations in trace elements levels were shown in chronically restrainted rats, the association between stress-induced changes in trace element levels and the effects of psychopharmacological agents has not been well documented yet. Tianeptine has been a widely used antidepressant in experimental studies investigating stress related behavioral changes. In this study, we aimed to search the effects of tianeptine pretreatment on stress-induced trace element alterations in rat brain.