Amyand's hernia is a very rare form of hernia in the inguinal hernia sac. Presently described is a case of Amyand's hernia complicated by acute appendicitis. A 62-year-old male patient presented at the emergency department with complaints of pain in the right inguinal region. He had acute appendicitis in the right inguinal hernia. An appendectomy was performed. Due to the high risk of infection, a mesh application was avoided. The patient was discharged on the rst postoperative day. The incidence of Amyand's hernia accompanied by acute appendicitis is quite low. The current literature generally does not recommended an Amyand's hernia mesh repair with a la- paroscopic appendectomy in the presence of acute appendicitis. In this case, the appendectomy was completed laparoscopically and the hernia sac was repaired intraperitoneally with primary suturing.