A Splenic Marginal Zone Lymphoma Case Presenting with Cyanosis, Spider Angiomas, and Polycythemia

Altunoglu E. G., Ar M. C., Tuzuner N., Saribeyoglu K.

ISTANBUL MEDICAL JOURNAL, vol.16, no.4, pp.158-161, 2015 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.5152/imj.2015.38233
  • Journal Name: ISTANBUL MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.158-161
  • Istanbul University Affiliated: Yes

Abstract

Splenic marginal zone lymphoma (SMZL) is an indolent cancer classified among low-grade B-cell lymphomas in the World Health Organization (WHO) classification. The major characteristics of SMZL are splenomegaly, villous cytoplasmic protrusions of the lymphocytes in peripheral blood, anemia, and/ or thrombocytopenia. The involvement of various organs, particularly the bone marrow or liver, can be frequently observed. SMZL has been reported to be associated with hepatitis C infection. The course of the disease is generally indolent, but aggressive behavior may be observed in a minority of patients. Here, we report a 43-year-old male hepatitis B virus carrier who presented with abdominal distension, multiple spider angiomas on the skin, and central cyanosis, leading to a diagnosis of SMZL.